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1.
Eiiti Kasuya 《Population Ecology》1993,35(2):251-255
An index of intensity of sexual selection proposed by Nishida (1992: Res. Popul. Ecol. 34: 373–382) was examined. Two examples were presented to show that Nishida's index was not free from confounding effect of mortality schedule. Importance of removing the phylogenetic effects in comparative analyses was also discussed. 相似文献
2.
In this paper, we propose an integrative framework to assess the conservation status of rare plant populations that combines population trends with four criteria to assess habitat vulnerability. We illustrate how population trends can be studied using a presence/absence method for a species that is inappropriate for a demographic study. The four other criteria concern habitat fragmentation, the human footprint in the surrounding landscape, observed impacts on a population and elements of habitat structure and quality that may impinge on population status. Each criterion is assessed with various indicators that can be adapted to the biology and ecology of the studied species. To test the feasibility of the proposed framework, we perform a case study of a Mediterranean geophyte Allium chamaemoly L., a species listed for protection in France. The results show a wide range of conservation status among a regional set of populations in the study species. Variation among the indicators used to assess different criteria illustrates the importance of assessing a range of different factors and ways to combine them if population conservation status is to be objectively identified. The study of diverse criteria may allow for a more precise assessment of the causes of differences in conservation status among populations of a single species. The framework of five criteria could be adapted by modification or substitution of indicators or adaptation of thresholds among classes, and thus be applied to other species of conservation importance. 相似文献
3.
Potential natural vegetation and pre‐anthropic pollen records on the Azores Islands in a Macaronesian context 下载免费PDF全文
This paper discusses the concept of potential natural vegetation (PNV) in the light of the pollen records available to date for the Macaronesian biogeographical region, with emphasis on the Azores Islands. The classical debate on the convenience or not of the PNV concept has been recently revived in the Canary Islands, where pollen records of pre‐anthropic vegetation seemed to strongly disagree with the existing PNV reconstructions. Contrastingly, more recent PNV model outputs from the Azores Islands show outstanding parallelisms with pre‐anthropic pollen records, at least in qualitative terms. We suggest the development of more detailed quantitative studies to compare these methodologies as an opportunity for improving the performance of both. PNV modelling may benefit by incorporating empirical data on past vegetation useful for calibration and validation purposes, whereas palynology may improve past reconstructions by minimizing interpretative biases linked to differential pollen production, dispersal and preservation. 相似文献
4.
The past few years have seen significant advances in our understanding of eukaryotic genomes. In the field of parasitology, this is best exemplified by the application of genome mapping techniques to the study of genome structure and function in the protozoan parasite, Leishmania. Although much is known about the organism and the diseases it causes, molecular genetics has only recently begun to play a major part in elucidating some of the unusual characteristics of this interesting parasite. Mapping of the small (35 Mb) genome and determination of the functional role of genes by the application of in vitro homologous gene targeting techniques are revealing novel avenues for the development of prophylactic measures. 相似文献
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Mayfly bioindicator thresholds for several anthropogenic disturbances in neotropical savanna streams
Anthropogenic disturbances are widely recognized as major threats to terrestrial and aquatic biodiversity worldwide, including areas located in non-forest ecosystems. Headwater streams in the neotropical savanna are severely threatened by large-scale landscape changes that degrade local habitat characteristics and lead to biodiversity loss. The objective of our study was to evaluate Ephemeroptera assemblages as bioindicators of catchment land use and cover, local streambed and riparian vegetation conditions, and instream water quality. To do so, we sampled mayfly nymphs in 184 stream sites across a broad disturbance gradient in four hydrologic units of the Brazilian neotropical savanna. We selected seven metrics without significant co-variation with natural variability: % catchment urban, riparian vegetation condition index (RCOND), human disturbances of the stream channel and riparian zone (W1_HALL), substrate mean embeddedness (XEMBED), dissolved oxygen (mg L−1), pH, and total phosphorus (mg L−1). We ran threshold indicator taxa analysis (TITAN) for each disturbance metric to detect change points in mayfly genera responses (whether sensitive or tolerant) and assemblage turnover pattern. TITAN showed that 20 of the 39 genera found were robust bioindicators (based on purity and reliability values >0.95), sixteen of them being sensitive to increased disturbance. The most sensitive genera were Tricorythopsis (Leptohyphidae) and Camelobaetidius (Baetidae), showing decreased abundance to most disturbance metrics. We found a turnover pattern of mayfly genera in response to W1_HALL in a narrow variation range. For total phosphorus, the benchmark value defined in Brazilian Federal Legislation is higher than the turnover threshold of several mayfly genera. This indicates that we will lose many sensitive genera even within the limits imposed by national environmental legislation. The indicator taxa approach, based on multiple taxa rather than univariate metrics or single indicator species, demonstrates the value of quantitative ecological information for conserving and managing freshwater ecosystems globally. 相似文献
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Natural antibodies to interferon-gamma 总被引:3,自引:0,他引:3
Natural antibodies to interferon (IFN)-γ were detected in the serum of virus-infected patients and also, at a low titre, in
the serum of healthy subjects. The increased titre of antibodies to IFN-γ in the sera of virus-infected patients, and its
decrease with clinical resolution, indicate that these antibodies are related to viral infection and probably reflect IFN-γ
production as a result of antigenic stimulationin vivo. Natural antibodies to IFN-γ were affinity purified and studied for their capability to interferein vitro with the multiple activities of the lymphokine. Data obtained show that these human anti-IFN-γ antibodies have no inhibitory
effect on the antiviral and antiproliferative activity of IFN-γ and do not interfere with the binding of the lymphokine to
its specific cell receptor. Instead, they can inhibit the expression of HLA-DR antigens induced by IFN-γ on U937 cells and
interfere, in mixed lymphocyte culture, with the proliferation of lymphocytes and the generation of cytotoxic lymphocytes.
Experiments in animal models suggest that natural antibodies to IFN-γ may have a role in the immunoregulatory process limiting
the intensity and/or duration of immune response. As they can interfere only with the immunomodulating activities of IFN-γ,
these antibodies might open up new therapeutic approaches to diseases with evidence of activated cell-mediated immunity. 相似文献
10.
Behnaz Valipour Kobra Velaei Ali Abedelahi Mohammad Karimipour Masoud Darabi Hojjatollah Nozad Charoudeh 《Journal of cellular physiology》2019,234(11):19352-19365
Natural killer (NK) cells have significant capability in tumor immune-surveillance. The ability of lyse transformed cells immediately in an antigen-independent manner make them an attractive candidate for cancer cell therapy. Despite employment of NK cells in cancer immunotherapy, clinical trials are faced with serious limitations such as trouble with the penetration of NK cells in tumor sites, limited in vivo persistence, and tumor microenvironment interference. Taken together, the NK-cell cancer therapy is still infant scenario that has a long way to be translated in clinic. Current article first reviews characteristic features of NK lymphocytes. Then, it discusses about important disruptive barriers and motivator in the developmental stages of NK cells like as tumor microenvironment. Finally, some revolutionary approaches are highlighted utilizing of NK cells in cancer therapy. 相似文献